As it is known, Fip disease in cats is a very serious and fatal disease. The disease is seen in 2 basic forms. These forms, which are called dry and wet Fip, can also be accompanied by ocular symptoms.
The drug gs441524, which was recently discovered by Dr Pedersen, has helped many cats with FIP to regain their health.
GENERAL QUESTIONS ABOUT GS-441524
What is GS-441524?
GS is short for GS-441524, a small molecule nucleotide analog. Perdersen NC from UC Davis (Global Veterinary No.1) and feline infectious peritonitis scientific research contact found to have a specific effect on FIP. It is a reverse transcriptase inhibitor that can inhibit the replication of bride infectious peritonitis (FIP) and is a prerequisite molecule for the synthesis of nucleoside triphosphates with pharmacological activity.
In the synthesis of FIPV virus RNA, GS-441524 is phosphorylated to active NTP through a set of cellular kinases in the cell that compete to participate in transcription of feline coronavirus RNA, thereby inhibiting virus replication in the body.
How is the drug used?
GS is used as a subcutaneous injection once a day (it should be done at the same time every day)
What is the treatment dose?
The dosage is calculated based on the specific symptoms of the cat
Wet FIP: 6mg/kg/day
Dry FIP:7mg/kg/day
Ocular form: 8mg/kg/day
Neurological form: 10mg/kg/day
Dosage can be increased depending on the cat's recovery and general condition.
Dosage should be adjusted depending on weight gain.
Treatment duration?
The recommended treatment period is 12 weeks. At the end of 12 weeks, the patient is evaluated in terms of blood and biochemical parameters and general symptoms. This period can be extended depending on the veterinarian's decision.
Should another drug be used in addition to the treatment?
Although GS-441524 is the drug used for the treatment of fip. Symptomatic treatment such as antibiotics, cortisone, vitamins and serum supplements may be required in addition to the treatment.
How should nutrition be?
In the early stage of FIP, cats will have fever and anorexia, leading to malnutrition and low immunity. Therefore, during treatment it is important to ensure adequate nutrition of the body and improve the body's immunity. In the first stage, severe anorexia occurs. When the loss of appetite improves, it is necessary to force-feed (canned food, nutrient solution). Do not cut back on nutrient solution, canned food and other nutrients after loss of appetite returns to normal.
Liver and kidney function
Both the cause of FIP disease and long-term medications place a relatively large strain on the liver and kidneys. Therefore, liver and kidney problems should not be ignored during treatment. It is especially important to protect the liver and prevent kidney failure. Liver and kidneys should be checked every 4 weeks.
Probiotic use
Some cats get diarrhea because the coronavirus invades the intestines first. It is recommended that yeast cooperate with probiotics to regulate the intestines and stomach.
Vitamins
Vitamins have a huge impact on cats. Adequate vitamin intake is beneficial for both sick FIP cats and healthy cats. It is recommended to supplement during the treatment period, which will greatly benefit the treatment and recovery of the body.
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